Efficacy assessment of a novel endolysin PlyAZ3aT for the treatment of ceftriaxone-resistant pneumococcal meningitis in an infant rat model
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DOI: 10.1371/journal.pone.0266928
Abstract: Background Treatment failure in pneumococcal meningitis due to antibiotic resistance is an increasing clinical challenge and alternatives to antibiotics warrant investigation. Phage-derived endolysins efficiently kill gram-positive bacteria including multi-drug resistant strains, making them attractive therapeutic… read more here.
Keywords: pneumococcal meningitis; treatment; ceftriaxone resistant; plyaz3at ... See more keywords