miR‐19b‐3p induces cell proliferation and reduces heterochromatin‐mediated senescence through PLZF in goat male germline stem cells
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DOI: 10.1002/jcp.26231
Abstract: Promyelocytic leukemia zinc finger PLZF, known as ZBTB16 or ZFP145 is a critical zinc finger protein of male germline stem cells (mGSCs), it's an essential transcriptional factor for goat testis development and spermatogenesis. Loss of… read more here.
Keywords: plzf; heterochromatin mediated; mir 19b; proliferation ... See more keywords
Regulation of the tumor suppressor PLZF and prostate cancer prognosis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.6_suppl.137
Abstract: 137Background: PLZF (ZBTB16) is an androgen-regulated tumor suppressor gene. Homozygous PLZF deletions are seen in a proportion of localized as well as castration-resistant prostate cancers (PC). Since PTEN has been shown to regulate PLZF expression… read more here.
Keywords: plzf; tumor suppressor; prostate; cancer ... See more keywords
Establishment of Murine Pregnancy Requires the Promyelocytic Leukemia Zinc Finger Transcription Factor
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DOI: 10.3390/ijms25063451
Abstract: Using an established human primary cell culture model, we previously demonstrated that the promyelocytic leukemia zinc finger (PLZF) transcription factor is a direct target of the progesterone receptor (PGR) and is essential for progestin-dependent decidualization… read more here.
Keywords: transcription factor; pregnancy; culture; plzf ... See more keywords