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   Articles with "pm2 induced" as a keyword



Genome-wide transcriptional analysis of cardiovascular-related genes and pathways induced by PM2.5 in human myocardial cells

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recommendations! Published in 2017 at "Environmental Science and Pollution Research"

DOI: 10.1007/s11356-017-8773-3

Abstract: Air pollution has been a major environment-related health threat. Most of the studies on PM2.5 toxicity have verified on the cardiovascular system and endothelial cells. However, researches on PM2.5-induced myocardial-related toxicity are limited. This study… read more here.

Keywords: pm2 human; analysis; toxicity; signaling pathway ... See more keywords

LncRNA Gm16410 regulates PM2.5-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.

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recommendations! Published in 2020 at "Ecotoxicology and environmental safety"

DOI: 10.1016/j.ecoenv.2020.111327

Abstract: Exposure to PM2.5 can cause serious harm to the respiratory system. Until now, although many toxicological studies have shown that pulmonary fibrosis can be caused by long-term PM2.5 exposure, there is no evidence that Endothelial-Mesenchymal… read more here.

Keywords: endothelial mesenchymal; gm16410; biology; lncrna gm16410 ... See more keywords

Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM2.5-induced lung injury in rats by modulating the NF-κB pathway.

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recommendations! Published in 2021 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2021.114420

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Andrographis paniculata (Burm.f.) Nees, a traditional Chinese herb, has been widely used in various Asian countries as a treatment for upper respiratory tract infections for centuries. AIM OF THE STUDY Continuous inhalation of… read more here.

Keywords: pm2; andrographis paniculata; induced lung; injury ... See more keywords

Metformin protects against PM2.5-induced lung injury and cardiac dysfunction independent of AMP-activated protein kinase α2

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recommendations! Published in 2019 at "Redox Biology"

DOI: 10.1016/j.redox.2019.101345

Abstract: Fine particulate matter (PM2.5) airborne pollution increases the risk of respiratory and cardiovascular diseases. Although metformin is a well-known antidiabetic drug, it also confers protection against a series of diseases through the activation of AMP-activated… read more here.

Keywords: metformin; cardiac dysfunction; lung injury; injury cardiac ... See more keywords

Sesamin Ameliorates Fine Particulate Matter (PM2.5)-Induced Lung Injury via Suppression of Apoptosis and Autophagy in Rats.

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recommendations! Published in 2022 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c02470

Abstract: Lung damage can be caused by fine particulate matter (PM2.5). Thus, effective prevention strategies for PM2.5-induced lung injury are urgently required. Sesamin (Ses) is a natural polyphenolic compound that has attracted considerable attention of researchers… read more here.

Keywords: apoptosis; lung injury; induced lung; pm2 ... See more keywords

Corneal biomechanical cues mediated by PAI-2: the origin of PM2.5-induced corneal disease.

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recommendations! Published in 2025 at "EMBO molecular medicine"

DOI: 10.1038/s44321-025-00341-0

Abstract: The biomechanical signature is directly correlated with the progression of disease in multiple soft tissues. However, their variations and roles, particularly during the initiation period of the disease, remain unclear. Here, we report that PM2.5… read more here.

Keywords: pm2; disease; pai; progression ... See more keywords

iTRAQ based proteomic analysis of PM2.5 induced lung damage

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recommendations! Published in 2019 at "RSC Advances"

DOI: 10.1039/c9ra00252a

Abstract: Research on biomarkers and pathways provides new diagnostic, preventive and therapeutic strategies for PM2.5 correlated lung diseases. read more here.

Keywords: analysis pm2; pm2 induced; itraq based; induced lung ... See more keywords

Metformin attenuates PM2.5-induced oxidative stress by inhibiting the AhR/CYP1A1 pathway in proximal renal tubular epithelial cells

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recommendations! Published in 2024 at "Toxicology Mechanisms and Methods"

DOI: 10.1080/15376516.2024.2378296

Abstract: Abstract The harmful effects of PM2.5 on human health, including an increased risk of chronic kidney disease (CKD), have raised a lot of attention, but the underlying mechanisms are unclear. We used the Shanghai Meteorological… read more here.

Keywords: oxidative stress; ahr cyp1a1; pm2 induced; cyp1a1 pathway ... See more keywords

Activation of Nrf2 signaling pathway by Tectoridin protects against ferroptosis in particulate matter-induced lung injury.

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recommendations! Published in 2023 at "British journal of pharmacology"

DOI: 10.1111/bph.16085

Abstract: BACKGROUND AND PURPOSE Our previous research showed that ferroptosis plays a crucial role in the pathophysiology of PM2.5-induced lung injury. The present study aimed to investigate the protective role of the Nrf2 signaling pathway and… read more here.

Keywords: lung injury; induced lung; injury; pm2 induced ... See more keywords

Effect of Ethyl Acetate Fraction from Eucommia ulmoides Leaves on PM2.5-Induced Inflammation and Cognitive Dysfunction

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recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/7157444

Abstract: This study aimed to evaluate the protective effect of the ethyl acetate from Eucommia ulmoides leaves (EFEL) on PM2.5-induced cognitive impairment in BALB/c mice. EFEL improved PM2.5-induced cognitive decline by improving spontaneous alternative behavioral and… read more here.

Keywords: inflammation; effect ethyl; brain; pm2 ... See more keywords

Lipoxin A4 regulates PM2.5-induced severe allergic asthma in mice via the Th1/Th2 balance of group 2 innate lymphoid cells.

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recommendations! Published in 2018 at "Journal of thoracic disease"

DOI: 10.21037/jtd.2018.03.02

Abstract: Background Urban particulate matter (PM) contributes to the increasing number of people with asthma, which is closely related to the development of industrialization. Especially, PM with an aerodynamic diameter of read more here.

Keywords: group innate; innate lymphoid; asthma mice; lymphoid cells ... See more keywords