Astragaloside IV inhibits PMA-induced EPCR shedding through MAPKs and PKC pathway
Sign Up to like & getrecommendations! Published in 2017 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2017.1306868
Abstract: Abstract Astragaloside IV (AS-IV), a main active substance isolated from Astragalus membranaceus Bunge, has been shown to have multiple pharmacological effects. Endothelial cell protein C receptor (EPCR) is a marker of inflammation, and is also… read more here.
Keywords: induced epcr; pma induced; pkc pathway; epcr ... See more keywords
Gold Nanoparticles Inhibit PMA-Induced MMP-9 Expression via microRNA-204-5p Upregulation and Deactivation of NF-κBp65 in Breast Cancer Cells
Sign Up to like & getrecommendations! Published in 2023 at "Biology"
DOI: 10.3390/biology12060777
Abstract: Objective: Breast cancer (BC) is the most common malignancy in females globally. Matrix metalloproteinase-9 (MMP-9) is crucial to the invasion, progression and spread of BC. Gold nanoparticles (AuNPs) have an anti-tumorigenic role, but their therapeutic… read more here.
Keywords: induced mmp; mmp expression; inhibit pma; pma induced ... See more keywords
P2X7 receptor regulates EMMPRIN and MMP‑9 expression through AMPK/MAPK signaling in PMA‑induced macrophages.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular medicine reports"
DOI: 10.3892/mmr.2018.9282
Abstract: The rupture of atherosclerotic plaques may result in the formation of thrombi, which may induce subsequent cardiac events such as acute myocardial infarction. Overproduction of matrix metalloproteinases (MMPs) and extracellular matrix metalloproteinase inducers (EMMPRINs) by… read more here.
Keywords: pma; pma induced; emmprin mmp; induced macrophages ... See more keywords