The plasma membrane Ca2+ pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells
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DOI: 10.1002/ijc.30503
Abstract: Oncogenic mutations of BRAF lead to constitutive ERK activity that supports melanoma cell growth and survival. While Ca2+ signaling is a well‐known regulator of tumor progression, the crosstalk between Ca2+ signaling and the Ras‐BRAF‐MEK‐ERK pathway… read more here.
Keywords: melanoma; braf mutant; mutant melanoma; pmca4b ... See more keywords