Diagnostic assessment of foetal brain malformations with intra-uterine MRI versus perinatal post-mortem MRI
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DOI: 10.1007/s00234-019-02218-9
Abstract: PurposeTo evaluate differences in diagnostic yield of intra-uterine foetal (iuMR) and post-mortem MRI (PMMR) for complex brain malformations, using autopsy as the reference standard.MethodsIn this retrospective, multicentre study spanning 2Â years, we reviewed 13 terminated singleton… read more here.
Keywords: brain malformations; pmmr; post mortem; mortem mri ... See more keywords
Lymphocytic response to tumour and deficient DNA mismatch repair identify subtypes of stage II/III colorectal cancer associated with patient outcomes
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DOI: 10.1136/gutjnl-2017-315664
Abstract: Objective Tumour-infiltrating lymphocyte (TIL) response and deficient DNA mismatch repair (dMMR) are determinants of prognosis in colorectal cancer. Although highly correlated, evidence suggests that these are independent predictors of outcome. However, the prognostic significance of… read more here.
Keywords: til low; pmmr; dmmr; til mmr ... See more keywords
Intertumoral Heterogeneity of CD3+ and CD8+ T-Cell Densities in the Microenvironment of DNA Mismatch-Repair–Deficient Colon Cancers: Implications for Prognosis
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DOI: 10.1158/1078-0432.ccr-18-1984
Abstract: Purpose: Colorectal cancers with deficient DNA mismatch repair (dMMR) are presumed to uniformly have dense lymphocytic infiltration that underlies their favorable prognosis and is critical to their responsiveness to immunotherapy, as compared with MMR-proficient (pMMR)… read more here.
Keywords: heterogeneity; dmmr; cell densities; pmmr ... See more keywords