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   Articles with "pmn mdsc" as a keyword



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Human splenic polymorphonuclear myeloid‐derived suppressor cells (PMN‐MDSC) are strategically located immune regulatory cells in cancer

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recommendations! Published in 2020 at "European Journal of Immunology"

DOI: 10.1002/eji.202048666

Abstract: In contrast to the mouse, functional assets of polymorphonuclear myeloid‐derived suppressor cells (PMN‐MDSC) in the human spleen remain to be better elucidated. Here, we report that the spleen in gastric and pancreatic cancer adopts an… read more here.

Keywords: pmn mdsc; immune regulatory; polymorphonuclear myeloid; cancer ... See more keywords
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Neutrophils and PMN-MDSC: Their biological role and interaction with stromal cells.

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recommendations! Published in 2018 at "Seminars in immunology"

DOI: 10.1016/j.smim.2017.12.004

Abstract: Neutrophils and polymorphonucler myeloid-derived suppressor cells (PMN-MDSC) share origin and many morphological and phenotypic features. However, they have different biological role. Neutrophils are one of the major mechanisms of protection against invading pathogens, whereas PMN-MDSC… read more here.

Keywords: pmn mdsc; interaction stromal; role; biological role ... See more keywords
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A new procedure to analyze polymorphonuclear myeloid derived suppressor cells in cryopreserved samples cells by flow cytometry

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recommendations! Published in 2018 at "PLoS ONE"

DOI: 10.1371/journal.pone.0202920

Abstract: Myeloid derived suppressor cells (MDSC) is a heterogeneous subset of immature and mature cells of the myeloid lineage, undergoing expansion during pathologic conditions, and able to perform strong immune suppressive functions. It has been shown… read more here.

Keywords: pmn mdsc; suppressor cells; derived suppressor; mdsc ... See more keywords
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Polymorphonuclear Myeloid-Derived Suppressor Cells Are Abundant in Peripheral Blood of Cancer Patients and Suppress Natural Killer Cell Anti-Tumor Activity

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recommendations! Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.803014

Abstract: Tumor microenvironment (TME) includes a wide variety of cell types and soluble factors capable of suppressing immune-responses. While the role of NK cells in TME has been analyzed, limited information is available on the presence… read more here.

Keywords: tumor; pmn mdsc; tumor activity; anti tumor ... See more keywords