Characterization of Clofazimine as a Potential Substrate of Drug Transporter
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DOI: 10.1128/aac.02158-21
Abstract: In this study, we explored clofazimine (CFZ) as a potential substrate of uptake and efflux transporters that might be involved in CFZ disposition, using transporter gene overexpressing cell lines in vitro. The intracellular concentrations of… read more here.
Keywords: cell lines; pmol min; min protein; potential substrate ... See more keywords
Time Course of Normalization of Functional β-Cell Capacity in the Diabetes Remission Clinical Trial After Weight Loss in Type 2 Diabetes
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DOI: 10.2337/dc19-0371
Abstract: OBJECTIVE To assess functional β-cell capacity in type 2 diabetes during 2 years of remission induced by dietary weight loss. RESEARCH DESIGN AND METHODS A Stepped Insulin Secretion Test with Arginine was used to quantify… read more here.
Keywords: remission; weight loss; cell capacity; pmol min ... See more keywords
Monocyte Metabolism and Function in Patients Undergoing Cardiac Surgery
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DOI: 10.3389/fcvm.2022.853967
Abstract: Objective Cardiopulmonary bypass (CPB) can lead to systemic inflammation, which is associated with higher morbidity. Therefore, we investigated the metabolism of isolated blood monocytes before and after CPB compared to healthy controls. Methods In this… read more here.
Keywords: metabolism; patients undergoing; pmol min; undergoing cardiac ... See more keywords