Bioinspired Polysaccharide‐Derived Zwitterionic Brush‐like Copolymer as an Injectable Biolubricant for Arthritis Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200090
Abstract: Developing highly efficient and biocompatible biolubricants for arthritis treatment is extraordinarily demanded. Herein, inspired by the efficient lubrication of synovial joints, a paradigm that combines natural polysaccharide (chitosan) with zwitterionic poly[2‐(methacryloyloxy) ethyl phosphorylcholine] (PMPC), to… read more here.
Keywords: arthritis treatment; lubrication; pmpc; chitosan pmpc ... See more keywords
A low friction, biphasic and boundary lubricating hydrogel for cartilage replacement.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2017.11.002
Abstract: Partial joint repair is a surgical procedure where an artificial material is used to replace localised chondral damage. These artificial bearing surfaces must articulate against cartilage, but current materials do not replicate both the biphasic… read more here.
Keywords: lubrication; hydrogel; partial joint; lubrication mechanisms ... See more keywords
Effects of a roughened femoral head and the locus of grafting on the wear resistance of the phospholipid polymer-grafted acetabular liner.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.12.025
Abstract: Although laboratory tests and mid-term clinical outcomes show the clinical safety and remarkable wear resistance of the highly cross-linked polyethylene (HXLPE) acetabular liner with a nanometer-scaled graft layer of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC), the wear resistance… read more here.
Keywords: head; hxlpe; femoral head; roughened femoral ... See more keywords
Thermal sensitivity and protein anti-adsorption of hydroxypropyl cellulose-g- poly(2-(methacryloyloxy) ethyl phosphorylcholine).
Sign Up to like & getrecommendations! Published in 2017 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2016.10.051
Abstract: Zwitterionic graft copolymers, hydroxypropyl cellulose graft poly(2-(methacryloyloxy) ethyl phosphorylcholine) (HPC-g-PMPC) with well-defined architecture were synthesized by atom transfer radical polymerization (ATRP). The self-assembly behaviors and thermal sensitivity of HPC-g-PMPC copolymers and their correlations with graft… read more here.
Keywords: poly methacryloyloxy; methacryloyloxy ethyl; graft; hydroxypropyl cellulose ... See more keywords
Fouling-resistant ultrafiltration membranes prepared via co-deposition of dopamine/zwitterion composite coatings
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Membrane Science"
DOI: 10.1016/j.memsci.2017.06.055
Abstract: Poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC), a polymer zwitterion, is known to reduce biofouling and impart low friction characteristics to materials surfaces. Using a one-step solution coating process, we report the incorporation of PMPC into polydopamine (PD) coatings… read more here.
Keywords: ultrafiltration membranes; pmpc modified; zwitterion; pmpc ... See more keywords
Synthesis and Characterization of Palmitoyl-block-poly(methacryloyloxyethyl Phosphorylcholine) Polymer Micelles for Anticancer Drug Delivery.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00838
Abstract: We report the synthesis and characterization of an amphiphilic polymer comprising a hydrophobic palmitoyl group and a zwitterionic poly(2-methacryloyloxyethyl phosphorylcholine) (pMPC) block, which is capable of forming micelles as a drug carrier system for delivering… read more here.
Keywords: block; polymer; palmitoyl; drug ... See more keywords
Phosphorylcholine-Based Polymer Encapsulated Chitosan Nanoparticles Enhance the Penetration of Antimicrobials in a Staphylococcal Biofilm
Sign Up to like & getrecommendations! Published in 2019 at "ACS Macro Letters"
DOI: 10.1021/acsmacrolett.9b00142
Abstract: Biofilms that contribute to the persistent bacterial infections pose serious threats to human health, due in part to the extracellular polymeric substances (EPS) matrix of biofilm block the diffusion of intact antimicrobials. The poor penetration… read more here.
Keywords: penetration antimicrobials; based polymer; biofilm; phosphorylcholine based ... See more keywords
Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions
Sign Up to like & getrecommendations! Published in 2022 at "Science and Technology of Advanced Materials"
DOI: 10.1080/14686996.2022.2146466
Abstract: ABSTRACT Liposome surface coating has been studied to avoid the immunological responses caused by the complement system, and alternative materials to poly(ethylene glycol) (PEG) have been explored recently since the production of anti-PEG IgM antibodies… read more here.
Keywords: pmpc; modification; pmpc lipids; surface ... See more keywords
Biocompatible Polymer-Grafted TiO2 Nanoparticle Sonosensitizers Prepared Using Phosphonic Acid-Functionalized RAFT Agent
Sign Up to like & getrecommendations! Published in 2023 at "Polymers"
DOI: 10.3390/polym15112426
Abstract: Sonodynamic therapy is widely used in clinical studies including cancer therapy. The development of sonosensitizers is important for enhancing the generation of reactive oxygen species (ROS) under sonication. Herein, we have developed poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC)-modified… read more here.
Keywords: phosphonic acid; pmpc modified; raft; acid functionalized ... See more keywords