Synthesis, characterization, computational and biological evaluation of pyrazole hydrazones as promising anti-inflammatory agents
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DOI: 10.1038/s41598-025-26088-9
Abstract: In this study, two pyrazole-based hydrazone derivatives, 5-methyl-1-phenyl-4-(1-(2-phenylhydrazineylidene)ethyl)-1H-pyrazole (PMPH) and 1-(4-fluorophenyl)-5-methyl-4-(1-(2-phenylhydrazineylidene)ethyl)-1H-pyrazole (4F-PMPH), were synthesized and the structures of the compounds were elucidated through FT-IR, 1H and 13C NMR, and mass spectral methods. The anti-inflammatory potential… read more here.
Keywords: characterization computational; computational biological; synthesis characterization; pmph ... See more keywords