Discovery of PMSA Derivative 11 as a Novel Lead Compound for Therapeutic Treatment of Osteoporosis In Vitro and In Vivo.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.3c00114
Abstract: To discover a potent candidate for suppressing mature osteoclasts formation in vitro using a TRAP staining assay. A series of PMSA derivatives were synthesized and evaluated for their bioactivity in our current study. Our results… read more here.
Keywords: vitro; lead compound; pmsa derivative; pmsa ... See more keywords
Sarcopenia in Children With End-Stage Liver Disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pediatric Gastroenterology and Nutrition"
DOI: 10.1097/mpg.0000000000001792
Abstract: Background: Sarcopenia, reflected by decreased psoas muscle surface area (PMSA), has been identified as a novel and independent predictor of wait-list mortality and outcomes in adult liver transplantation (LT). We hypothesized that children with end-stage… read more here.
Keywords: stage liver; pmsa; children end; liver disease ... See more keywords
Experimental validation of a mean systemic pressure analog against zero-flow measurements in porcine VA-ECMO.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00804.2021
Abstract: The mean systemic pressure analog (Pmsa) calculated from running hemodynamic data, estimates mean systemic filling pressure (MSFP). This post hoc study used data from a porcine veno-arterial extra-corporeal membrane oxygenation (ECMO) model [n=9; Sus scrofa… read more here.
Keywords: mean systemic; pressure; pmsa; systemic pressure ... See more keywords