PEG-free Lipid Nanoparticles for mRNA Delivery: Superhydrophilic Sulfoxide Polymer Coatings.
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DOI: 10.1021/acs.biomac.5c01899
Abstract: Lipid nanoparticles (LNPs) are the most widely applied nanocarriers for mRNA delivery in clinical use. However, the limited stability and increasingly recognized immunogenicity of PEG-based LNP formulations are potential impediments to the more widespread development… read more here.
Keywords: pmsea; delivery; mrna delivery; polymer coatings ... See more keywords