Liraglutide-Conjugated Poly(methyl vinyl ether-alt-maleic acid)-Coated Core–Shell Upconversion Nanoparticles for Theranostics of Diabetes
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DOI: 10.1021/acsami.5c11275
Abstract: In the diagnostics of diabetes, specific targeting of drugs (e.g., liraglutide) to insulin-deficient β-cells with their simultaneous noninvasive imaging is currently needed. In this report, liraglutide (LGL)-conjugated poly(methyl vinyl ether-alt-maleic acid) (PMVEMA)-coated core–shell NaYF4:Yb,Er,Fe@NaYF4:Nd upconversion… read more here.
Keywords: vinyl ether; methyl vinyl; pmvema; upconversion ... See more keywords
Chemical and Colloidal Stability of Polymer-Coated NaYF4:Yb,Er Nanoparticles in Aqueous Media and Viability of Cells: The Effect of a Protective Coating
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DOI: 10.3390/ijms24032724
Abstract: Upconverting nanoparticles (UCNPs) are of particular interest in nanomedicine for in vivo deep-tissue optical cancer bioimaging due to their efficient cellular uptake dependent on polymer coating. In this study, particles, ca. 25 nm in diameter,… read more here.
Keywords: polymer; dissolution; ale pdma; peg ... See more keywords
Electrospun PMVEMA Nanofibers Developed as a Fast-Release Platform for Antineoplastic Drugs Tested in Glioblastoma Primary Cultures
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DOI: 10.3390/pharmaceutics17091172
Abstract: Background/Objectives: The local release of antineoplastic drugs in post-surgical treatments is an alternative way to improve their effectiveness against glioblastoma reappearance. Thus, it was proposed to develop a local delivery system based on electrospun PMVEMA-derived… read more here.
Keywords: electrospun pmvema; dox; release; pmvema ... See more keywords