Closing the Loop: Constraining TAT Peptide by γPNA Hairpin for Enhanced Cellular Delivery of Biomolecules.
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DOI: 10.1021/acs.bioconjchem.8b00495
Abstract: Based on the exceptionally high stability of γPNA duplexes, we designed a peptide/γPNA chimera in which a cell-penetrating TAT peptide is flanked by two short complementary γPNA segments. Intramolecular hybridization of the γPNA segments results… read more here.
Keywords: tat peptide; pna hairpin; peptide pna; pna ... See more keywords