Facile Preparation of PNA-Peptide Conjugates with a Polar Maleimide-Thioether Linkage.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0243-0_6
Abstract: Conjugation of a delivery peptide containing a thiol functionality (e.g., a cysteine residue) with a PNA oligomer displaying a single unprotected aliphatic primary amine (e.g., the N-terminus or a C-terminal lysine residue) can be achieved… read more here.
Keywords: pna peptide; pna; peptide conjugates; preparation pna ... See more keywords
Antimicrobial activity of antisense peptide–peptide nucleic acid conjugates against non-typeable Haemophilus influenzae in planktonic and biofilm forms
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkw384
Abstract: Background Antisense peptide nucleic acids (PNAs) are synthetic polymers that mimic DNA/RNA and inhibit bacterial gene expression in a sequence-specific manner. Methods To assess activity against non-typeable Haemophilus influenzae (NTHi), we designed six PNA-peptides that… read more here.
Keywords: peptide; pna peptide; pna; peptide nucleic ... See more keywords