Targeting a KRAS i‐motif forming sequence by unmodified and gamma‐modified peptide nucleic acid oligomers
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DOI: 10.1002/bip.23529
Abstract: Growing interest in i‐motif DNA as a transcriptional regulatory element motivates development of synthetic molecules capable of targeting these structures. In this study, we designed unmodified peptide nucleic acid (PNA) and gamma‐modified PNA (γPNA) oligomers… read more here.
Keywords: spectroscopy; motif forming; pna pna; sequence ... See more keywords