Genetic background impacts vaccine-induced reduction of pneumococcal colonization.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.08.023
Abstract: Vaccination has been one of the most successful strategies to reduce morbidity and mortality caused by respiratory infections. Recent evidence suggests that differences in the host genetic background and environmental factors may contribute to heterogeneity… read more here.
Keywords: reduction; pneumococcal colonization; genetic background; colonization ... See more keywords
2340. Pneumococcal Colonization in Pediatric Patients Undergoing Bone Marrow Transplantation
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.1993
Abstract: Abstract Background Hematopoietic cell transplant (HCT) recipients are at a significantly greater risk for invasive pneumococcal disease than the general population. However, pneumococcal colonization in pediatric HCT recipients has not been widely studied. We evaluated… read more here.
Keywords: pneumococcal colonization; colonization pediatric; patients undergoing; colonization ... See more keywords
Two Randomized Trials of the Effect of Live Attenuated Influenza Vaccine on Pneumococcal Colonization
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DOI: 10.1164/rccm.201811-2081le
Abstract: The human nasopharynx is frequently colonized by Streptococcus pneumoniae (the pneumococcus), serving as the reservoir for transmission, a state which necessarily precedes invasive pneumococcal infection. Influenza infection increases pneumococcal colonization density and dysregulates host immune… read more here.
Keywords: two randomized; trials effect; colonization; pneumococcal colonization ... See more keywords
IL-17 signalling restructures the nasal microbiome and drives dynamic changes following Streptococcus pneumoniae colonization
Sign Up to like & getrecommendations! Published in 2017 at "BMC Genomics"
DOI: 10.1186/s12864-017-4215-3
Abstract: BackgroundThe bacterial pathogen Streptococcus pneumoniae colonizes the nasopharynx prior to causing disease, necessitating successful competition with the resident microflora. Cytokines of the IL-17 family are important in host defence against this pathogen but their effect… read more here.
Keywords: pneumococcal colonization; nasal microbiome; streptococcus pneumoniae; colonization ... See more keywords