Pneumococcal Serotype-specific Opsonophagocytic Activity in Interleukin-1 Receptor-associated Kinase 4-deficient Patients.
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DOI: 10.1097/inf.0000000000003060
Abstract: BACKGROUND The antibody response after pneumococcal vaccines and their effectiveness against invasive pneumococcal disease (IPD) in patients with interleukin-1 receptor-associated kinase 4 (IRAK4) deficiency have not been fully evaluated. Here, we evaluated pneumococcal serotype-specific opsonophagocytic… read more here.
Keywords: interleukin receptor; pneumococcal serotype; associated kinase; deficient patients ... See more keywords
An Experimental Human Colonization Model with Pneumococcal Serotype 3 has the Potential to be Used for Vaccine Studies
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DOI: 10.1164/rccm.202207-1342ed
Abstract: pollution and pediatric respiratory hospitalizations: effect modification by particle constituents and oxidative potential. Am J Respir Crit Care Med 2022;206:1370–1378. 13. WuY, Li S, Guo Y. Space-time-stratified case-crossover design in environmental epidemiology study.Health Data Science… read more here.
Keywords: pneumococcal serotype; colonization model; human colonization; experimental human ... See more keywords
Evolution of pneumococcal serotype epidemiology in Botswana following introduction of 13-valent pneumococcal conjugate vaccine
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DOI: 10.1371/journal.pone.0262225
Abstract: Pneumococcal conjugate vaccines reduce the burden of invasive pneumococcal disease, but the sustained effect of these vaccines can be diminished by an increase in disease caused by non-vaccine serotypes. To describe pneumococcal serotype epidemiology in… read more here.
Keywords: pneumococcal serotype; introduction; pneumococcal conjugate; vaccine ... See more keywords
A spitting image: molecular diagnostics applied to saliva enhance detection of Streptococcus pneumoniae and pneumococcal serotype carriage
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DOI: 10.3389/fmicb.2023.1156695
Abstract: Background Despite strong historical records on the accuracy of saliva testing, oral fluids are considered poorly suited for pneumococcal carriage detection. We evaluated an approach for carriage surveillance and vaccine studies that increases the sensitivity… read more here.
Keywords: culture; pneumococcal serotype; saliva samples; detection ... See more keywords