The trophic life cycle stage of Pneumocystis species induces protective adaptive responses without inflammationâmediated progression to pneumonia
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DOI: 10.1093/mmy/myx145
Abstract: Abstract Pneumocystis species are fungal pathogens that cause pneumonia in immunocompromised hosts. Lung damage during Pneumocystis pneumonia is predominately due to the inflammatory immune response. Pneumocystis species have a biphasic life cycle. Optimal innate immune… read more here.
Keywords: pneumocystis; pneumocystis species; life cycle; pneumonia ... See more keywords
Analysis of Pneumocystis Transcription Factor Evolution and Implications for Biology and Lifestyle
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DOI: 10.1128/mbio.02711-22
Abstract: Pneumocystis jirovecii is a major fungal pathogen of humans that infects healthy individuals, colonizing the lungs of infants. In immunocompromised and transplant patients, this fungus causes life-threatening pneumonia, and these Pneumocystis infections remain among the… read more here.
Keywords: pneumocystis species; pneumocystis; biology; transcription factor ... See more keywords
Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of Multiple Pneumocystis Species
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DOI: 10.1128/mbio.02878-19
Abstract: Pneumocystis continues to be a major cause of disease in humans with immunodeficiency, especially those with HIV/AIDS and organ transplants, and is being seen with increasing frequency worldwide in patients treated with immunodepleting monoclonal antibodies.… read more here.
Keywords: pneumocystis species; diversity complexity; biology; pneumocystis ... See more keywords
Predicting Species Boundaries and Assessing Undescribed Diversity in Pneumocystis, an Obligate Lung Symbiont
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DOI: 10.3390/jof8080799
Abstract: Far more biodiversity exists in Fungi than has been described, or could be described in several lifetimes, given current rates of species discovery. Although this problem is widespread taxonomically, our knowledge of animal-associated fungi is… read more here.
Keywords: species boundaries; diversity; pneumocystis; pneumocystis obligate ... See more keywords