Triosephosphate isomerase of Streptococcus pneumoniae is released extracellularly by autolysis and binds to host plasminogen to promote its activation
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DOI: 10.1002/2211-5463.13396
Abstract: Recruitment of plasminogen is an important infection strategy of the human pathogen Streptococcus pneumoniae to invade host tissues. In Streptococcus aureus, triosephosphate isomerase (TPI) has been reported to bind plasminogen. In this study, the TPI of S. pneumoniae… read more here.
Keywords: autolysis binds; triosephosphate isomerase; pneumoniae; plasminogen ... See more keywords
Data‐Driven Engineering of Phages with Tunable Capsule Tropism for Klebsiella pneumoniae
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DOI: 10.1002/advs.202309972
Abstract: Klebsiella pneumoniae, a major clinical pathogen known for causing severe infections, is attracting heightened attention due to its escalating antibiotic resistance. Phages are emerging as a promising alternative to antibiotics; however, their specificity to particular… read more here.
Keywords: capsule tropism; klebsiella pneumoniae; pneumoniae;
Identification of Mycoplasma pneumoniae by DNA‐modified gold nanomaterials in a colorimetric assay
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DOI: 10.1002/bab.2377
Abstract: Mycoplasma pneumoniae is a highly infectious bacterium and the major cause of pneumonia especially in school‐going children. Mycoplasma pneumoniae affects the respiratory tract, and 25% of patients experience health‐related problems. It is important to have… read more here.
Keywords: dna; pneumoniae; gnps; target dna ... See more keywords
Synthetic Klebsiella pneumoniae-Shewanella oneidensis Consortium Enables Glycerol-Fed High-Performance Microbial Fuel Cells.
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DOI: 10.1002/biot.201700491
Abstract: Microbial fuel cell (MFC) is an eco-friendly bio-electrochemical sys-tem that uses microorganism as biocatalyst to convert biomass into electricity. Glycerol, as a waste in the biodiesel refinery processes, is an appealing substrate for MFC. Nevertheless,… read more here.
Keywords: consortium; shewanella oneidensis; pneumoniae; glycerol ... See more keywords
Near-infrared photodynamic inactivation of S. pneumoniae and its interaction with RAW 264.7 macrophages.
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DOI: 10.1002/jbio.201600283
Abstract: Pneumonia is the main cause of children mortality worldwide, and its major treatment obstacle stems from the microorganisms increasing development of resistance to several antibiotics. Photodynamic therapy has been presenting, for the last decades, promising… read more here.
Keywords: raw 264; 264 macrophages; near infrared; pneumoniae ... See more keywords
The making of hypervirulent Klebsiella pneumoniae
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DOI: 10.1002/jcla.24743
Abstract: Klebsiella pneumoniae is a notorious bacterium in clinical practice. Virulence, carbapenem‐resistance and their convergence among K. pneumoniae are extensively discussed in this article. Hypervirulent K. pneumoniae (HvKP) has spread from the Asian Pacific Rim to… read more here.
Keywords: making hypervirulent; pneumoniae; hypervirulent klebsiella; klebsiella pneumoniae ... See more keywords
Phenotypic, Targeted Genotypic, and Antimicrobial Susceptibility Profiling of Extended‐Spectrum β‐Lactamase Production and Exclusive bla OXA −48 Gene Detection in Escherichia coli and Klebsiella pneumoniae Isolates From a South Lebanese Hospital
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DOI: 10.1002/jcla.70108
Abstract: Globally, multidrug resistance (MDR), including extended‐spectrum β‐lactamase (ESBL) and carbapenemase production in Enterobacteriaceae, is increasing. Data concerning their presence in South Lebanon are scarce. This study aimed to determine the prevalence of ESBL and carbapenem‐resistant… read more here.
Keywords: escherichia coli; pneumoniae; extended spectrum; spectrum lactamase ... See more keywords
Prevalence of insertion sequence elements in plasmids relating to mgrB gene disruption causing colistin resistance in Klebsiella pneumoniae
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DOI: 10.1002/mbo3.1262
Abstract: Colistin is a last resort antibiotic for the treatment of carbapenemase producing Klebsiella pneumoniae. The disruption of the mgrB gene by insertion sequences (ISs) is a mechanism mediating colistin resistance. Plasmids encode mobilizable IS elements… read more here.
Keywords: mgrb gene; pneumoniae; gene; colistin resistance ... See more keywords
Genomic analyses of an Escherichia coli and Klebsiella pneumoniae urinary tract co‐infection using long‐read nanopore sequencing
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DOI: 10.1002/mbo3.1396
Abstract: Escherichia coli and Klebsiella pneumoniae isolates presenting with the same antimicrobial susceptibility profile were recovered from the same catheter sample of urine (CSU). Both strains were recovered from a patient with a long‐standing indwelling urinary… read more here.
Keywords: escherichia coli; resistance; klebsiella pneumoniae; pneumoniae ... See more keywords
Genomic Characterization of Pan‐Drug Resistant Klebsiella pneumoniae KPNW Isolated From UTI Patient in Bangladesh
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DOI: 10.1002/mbo3.70064
Abstract: Klebsiella pneumoniae is a Gram‐negative opportunistic bacterial pathogen and a common cause of urinary tract infections (UTIs). In Bangladesh, a rapid increase in antibiotic resistance in K. pneumoniae, with a concerning prevalence of pan‐drug resistant… read more here.
Keywords: pan drug; resistance; klebsiella pneumoniae; kpnw ... See more keywords
Discovering interrelated natural mutations of efflux pump KmrA from Klebsiella pneumoniae that confer increased multidrug resistance
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DOI: 10.1002/pro.4323
Abstract: Klebsiella pneumoniae is a notorious pathogen that can cause multiorgan infections, which is difficult to treat mainly due to the widely distributed efflux pumps. Our previous research discovered the upregulation of efflux pump KmrA conferred… read more here.
Keywords: pneumoniae; klebsiella pneumoniae; natural mutations; resistance ... See more keywords