Identification and molecular characterization of penicillin‐nonsusceptible Streptococcus pneumoniae isolates recovered from invasive infections in a pre‐pneumococcal vaccine era
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24566
Abstract: Given the significant role of penicillin‐nonsusceptible Streptococcus pneumoniae in inducing severe infectious diseases, identifying serotypes and genotypes that can mediate antimicrobial resistance has become a pillar of treatment strategies. This study aims to determine the… read more here.
Keywords: penicillin; penicillin nonsusceptible; nonsusceptible streptococcus; pneumoniae isolates ... See more keywords
Virulence genes, capsular and plasmid types of multidrug-resistant CTX-M(-2, -8, -15) and KPC-2-producing Klebsiella pneumoniae isolates from four major hospitals in Brazil.
Sign Up to like & getrecommendations! Published in 2018 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2018.01.007
Abstract: We performed a single-month snapshot study of the population diversity of multidrug resistant (MDR) Klebsiella pneumoniae isolates producing carbapenemases and/or extended-spectrum β-lactamases from four major hospitals in Brazil. Isolates produced diverse ESBL (CTX-M-2, -8, -15,… read more here.
Keywords: ctx; pneumoniae; multidrug resistant; klebsiella pneumoniae ... See more keywords
Core genome MLST and resistome analysis of Klebsiella pneumoniae using a clinically amenable workflow.
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2020.114996
Abstract: Whole genome sequencing (WGS) is replacing traditional microbiological typing methods for investigation of outbreaks in clinical settings. Here, we used a clinical microbiology laboratory core genome multilocus sequence typing (cgMLST) workflow to analyze 40 isolates… read more here.
Keywords: microbiology; pneumoniae isolates; pneumoniae; core genome ... See more keywords
MIC Profiling of Ceftazidime-Avibactam against two Carbapenemase producing Klebsiella pneumoniae Isolates.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2020.10.014
Abstract: OBJECTIVE To correlate results of a modified susceptibility testing method to outcomes of ceftazidime-avibactam (CAZ/AVI) therapy. METHODS Two bloodstreamK. pneumoniae isolates (CAZ/AVI susceptible) from an abdominal source were recovered from 2 unrelated patients. Both patients… read more here.
Keywords: ceftazidime avibactam; caz avi; mic profiling; caz ... See more keywords
Molecular insights of Carbapenem resistance Klebsiella pneumoniae isolates with focus on multidrug resistance from clinical samples.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of infection and public health"
DOI: 10.1016/j.jiph.2020.09.018
Abstract: BACKGROUND Carbapenem are the last-line antibiotic, defence against Gram-negative extended spectrum ß-lactamases producers (ESBLs). Carbapenem resistance Enterobacteriaceae especially Carbapenem resistant-Klebsiella pneumoniae (CR-KP) is recognized as one of the well-known public health problem, which is increasingly… read more here.
Keywords: pneumoniae; carbapenem resistance; resistance; klebsiella pneumoniae ... See more keywords
Molecular diversity and profile analysis of virulence-associated genes in some Klebsiella pneumoniae isolates
Sign Up to like & getrecommendations! Published in 2020 at "Practical Laboratory Medicine"
DOI: 10.1016/j.plabm.2020.e00152
Abstract: The noticeable increase in the occurrence of multidrug-resistant Klebsiella pneumoniae strains separated from different hospitals in Taif city, (Saudi Arabia) demonstrates the limitation of antibiotics used for bacterial eradication. The aim of the present study… read more here.
Keywords: virulence; analysis; pneumoniae; molecular diversity ... See more keywords
Identification of a newly isolated lytic bacteriophage against K24 capsular type, carbapenem resistant Klebsiella pneumoniae isolates
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-62691-8
Abstract: The increasing incidence of carbapenemase-producing K. pneumoniae strains (CP-Kps) in the last decade has become a serious global healthcare problem. Therapeutic options for the treatment of emerging hospital clones have drastically narrowed and therefore novel… read more here.
Keywords: pneumoniae; identification newly; bacteriophage; lytic bacteriophage ... See more keywords
1313. MIC Profiling of Ceftazidime-Avibactam (CAZ/AVI) Against Two Carbapenemase producing Klebsiella pneumoniae Isolates
Sign Up to like & getrecommendations! Published in 2020 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaa439.1495
Abstract: Carbapenemases confer resistance against a broad range of beta-lactams with a prevalence of 40-60% among CRE (carbapenem-resistant Enterobacteriaceae). CAZ-AVI is commonly used to treat infections due to CPE (carbapenemase-producing Enterobacteriaceae), typically guided by susceptibility testing… read more here.
Keywords: carbapenemase producing; caz avi; mic profiling; caz ... See more keywords
Trends in Streptococcus pneumoniae Antimicrobial Resistance in US Children: A Multicenter Evaluation
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DOI: 10.1093/ofid/ofad098
Abstract: Abstract Background Antimicrobial resistance (AMR) poses a significant challenge for treating pneumococcal disease. This study assessed AMR trends in Streptococcus pneumoniae from US children. Methods We evaluated antibiotic resistance, defined as facility antimicrobial susceptibility reports… read more here.
Keywords: resistance; trends streptococcus; antimicrobial resistance; drug ... See more keywords
Antibiotic resistance profiles and multidrug resistance patterns of Streptococcus pneumoniae in pediatrics
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000015942
Abstract: Abstract Emergent resistance to antibiotics among Streptococcus pneumoniae isolates is a severe problem worldwide. Antibiotic resistance profiles for S pneumoniae isolates identified from pediatric patients in mainland China remains to be established. The clinical features,… read more here.
Keywords: multidrug resistance; pneumoniae isolates; streptococcus pneumoniae; resistance ... See more keywords
Epidemiological typing of multidrug‐resistant Klebsiella pneumoniae, which causes paediatric ventilator‐associated pneumonia in Egypt
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medical Microbiology"
DOI: 10.1099/jmm.0.000473
Abstract: Purpose. Multidrug‐resistant Klebsiella pneumoniae is a common nosocomial pathogen that plays an important role in ventilator‐associated pneumonia (VAP). This study aimed to define the clonal relatedness of K. pneumoniae strains isolated from paediatric VAP in… read more here.
Keywords: pneumoniae; ventilator associated; multidrug resistant; klebsiella pneumoniae ... See more keywords