Local outbreak of Streptococcus pneumoniae serotype 12F caused high morbidity and mortality among children and adults
Sign Up to like & getrecommendations! Published in 2018 at "Epidemiology and Infection"
DOI: 10.1017/s0950268818002133
Abstract: Abstract Pneumococcal serotype replacement is an important issue after the introduction of pneumococcal conjugate vaccine (PCV) in children. After the introduction of 13-valent PCV, the incidence of invasive pneumococcal diseases (IPD) caused by Streptococcus pneumoniae… read more here.
Keywords: serotype 12f; streptococcus pneumoniae; pcv; valent pcv ... See more keywords
Frequent Transmission of Streptococcus pneumoniae Serotype 35B and 35D, Clonal Complex 558 Lineage, across Continents and the Formation of Multiple Clades in Japan
Sign Up to like & getrecommendations! Published in 2023 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01083-22
Abstract: Streptococcus pneumoniae is a common bacterial pathogen that causes infections in children worldwide, even after administration of the pneumococcal conjugate vaccine. S. pneumoniae serotype 35B, especially the clonal complex 558 (CC558) lineage, has emerged globally… read more here.
Keywords: pneumoniae; pneumoniae serotype; clonal complex; serotype 35b ... See more keywords
Human Intelectin-1 Promotes Cellular Attachment and Neutrophil Killing of Streptococcus pneumoniae in a Serotype-Dependent Manner
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DOI: 10.1128/iai.00682-21
Abstract: Human intelectin-1 (hIntL-1) is a secreted glycoprotein capable of binding exocyclic 1,2-diols within surface glycans of human pathogens such as Streptococcus pneumoniae, Vibrio cholerae, and Helicobacter pylori. For the latter, lectin binding was shown to… read more here.
Keywords: hintl; pneumoniae serotype; dependent manner; human intelectin ... See more keywords
Whole genomic comparative analysis of Streptococcus pneumoniae serotype 1 isolates causing invasive and non-invasive infections among children under 5 years in Casablanca, Morocco
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DOI: 10.1186/s12864-020-07316-0
Abstract: Background Streptococcus pneumoniae serotype 1 remains a leading cause of invasive pneumococcal diseases, even in countries with PCV-10/PCV-13 vaccine implementation. The main objective of this study, which is part of the Pneumococcal African Genome project… read more here.
Keywords: analysis; casablanca morocco; streptococcus pneumoniae; serotype ... See more keywords
Biochemical Characterization and Synthetic Application of WciN and Its Mutants From Streptococcus pneumoniae Serotype 6B
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DOI: 10.3389/fchem.2022.914698
Abstract: The biochemical properties of α-1,3-galactosyltransferase WciN from Streptococcus pneumoniae serotype 6B were systemically characterized with the chemically synthesized Glcα-PP-(CH2)11-OPh as an acceptor substrate. The in vitro site-directed mutation of D38 and A150 residues of WciN… read more here.
Keywords: biochemical characterization; characterization synthetic; pneumoniae serotype; wcin mutants ... See more keywords
Identification of a Novel Keto Sugar Component in Streptococcus pneumoniae Serotype 12F Capsular Polysaccharide and Impact on Vaccine Immunogenicity.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of immunology"
DOI: 10.4049/jimmunol.2100849
Abstract: Implementation of conjugate vaccine technology revolutionized the ability to effectively elicit long-lasting immune responses to bacterial capsular polysaccharides. Although expansion of conjugate vaccine serotype coverage is designed to target residual disease burden to pneumococcal serotypes… read more here.
Keywords: serotype 12f; pneumoniae serotype; keto sugar; vaccine ... See more keywords