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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0176204
Abstract: Background Legionella pneumophila (L. pneumophila) is a causative agent of severe pneumonia. It is highly adapted to intracellular replication and manipulates host cell functions like vesicle trafficking and mRNA translation to its own advantage. However,…
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Keywords:
legionella;
pneumophila infection;
myd88;
legionella pneumophila ... See more keywords
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Published in 2020 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2020.00428
Abstract: Legionella pneumophila is an environmental bacterium that has evolved to survive predation by soil and water amoebae such as Acanthamoeba castellanii, and this has inadvertently led to the ability of L. pneumophila to survive and…
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Keywords:
castellanii;
pneumophila infection;
infection;
acanthamoeba castellanii ... See more keywords
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Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11080908
Abstract: Legionella pneumophila is an accidental pathogen that replicates intracellularly within the Legionella-containing vacuole (LCV) in macrophages. Within an hour of infection, L. pneumophila secretes effectors to manipulate Rab1 and intercept ER-derived vesicles to the LCV.…
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Keywords:
legionella pneumophila;
infection;
golgi;
human macrophages ... See more keywords