Vasculocentric Axonal NfH in Small Vessel Disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuropathology and Experimental Neurology"
DOI: 10.1093/jnen/nlab134
Abstract: Abstract Cerebral small vessel disease (SVD) causes lacunar stroke and vascular cognitive impairment in older people. The pathogenic pathways from vessel pathology to parenchymal damage in SVD are unknown. Neurofilaments are axonal structural proteins. Neurofilament-light… read more here.
Keywords: axonal pnfh; vasculocentric axonal; disease; small vessel ... See more keywords
Validation of serum neurofilaments as prognostic and potential pharmacodynamic biomarkers for ALS
Sign Up to like & getrecommendations! Published in 2020 at "Neurology"
DOI: 10.1212/wnl.0000000000009559
Abstract: Objective To identify preferred neurofilament assays and clinically validate serum neurofilament light (NfL) and phosphorylated neurofilament heavy (pNfH) as prognostic and potential pharmacodynamic biomarkers relevant to amyotrophic lateral sclerosis (ALS) therapy development. Methods In this… read more here.
Keywords: serum nfl; serum; pnfh; prognostic potential ... See more keywords