Steroid Receptor Coactivator‐1 Drives Tumor‐Associated Macrophage Reprogramming by Mediating MMP12 Transcription in Pancreatic Cancer Perineural Invasion
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DOI: 10.1002/advs.202416575
Abstract: Perineural invasion (PNI) is a hallmark of pancreatic cancer aggressiveness. However, the feasibility of manipulating tumor‐associated macrophage (TAM) reprogramming to influence PNI development remains unclear. Methods: Using in vitro (tumor‐DRG co‐culture) and in vivo (sciatic… read more here.
Keywords: pni; perineural invasion; tumor; pancreatic cancer ... See more keywords
Impact of the pretreatment prognostic nutritional index on the survival after first-line immunotherapy in non-small-cell lung cancer patients.
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DOI: 10.1002/cam4.6110
Abstract: BACKGROUND Immunotherapy has become a standard-of-care for patients with non-small-cell lung cancer (NSCLC). Although several biomarkers, such as programmed cell death-1, have been shown to be useful in selecting patients likely to benefit from immune… read more here.
Keywords: cell; non small; pni; first line ... See more keywords
THE VALUE OF PROGNOSTIC NUTRITIONAL INDEX AT DIAGNOSIS IN PATIENTS WITH FOLLICULAR LYMPHOMA: A RETROSPECTIVE COHORT STUDY
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DOI: 10.1002/hon.2439_130
Abstract: Introduction: The clinical course and prognosis of follicular lymphoma (FL) is diverse. Studies about prognostic nutritional index (PNI), a marker of host inflammatory and nutritional status, indicated that it is associated with prognosis in a… read more here.
Keywords: diagnosis; follicular lymphoma; value; pni ... See more keywords
The predictive value of a preoperative systemic immune‐inflammation index and prognostic nutritional index in patients with esophageal squamous cell carcinoma
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DOI: 10.1002/jcp.27052
Abstract: Growing evidence indicates that systemic inflammation response and malnutrition status are correlated with survival in certain types of solid tumors. The aim of this study is to evaluate the association between the systemic immune‐inflammation index… read more here.
Keywords: sii; index; immune inflammation; systemic immune ... See more keywords
Preoperative Prognostic Nutritional Index Predicts Long-Term Surgical Outcomes in Patients with Esophageal Squamous Cell Carcinoma
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DOI: 10.1007/s00268-017-4437-1
Abstract: BackgroundThe purpose of the present study is to investigate the utility of prognostic nutritional index (PNI) as a simple and readily available marker in esophageal squamous cell carcinoma (ESCC).MethodsWe retrospectively analyzed 169 patients who underwent… read more here.
Keywords: cell carcinoma; squamous cell; pni; prognostic nutritional ... See more keywords
Prognostic nutritional index (PNI) correlates with survival in head and neck cancer patients more precisely than other nutritional markers – real world data
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DOI: 10.1007/s00405-024-08865-w
Abstract: The survival benefit with higher body mass index (BMI) of patients suffering from head and neck squamous cell carcinoma (HNSCC) is documented as BMI paradox. As the early re-nourishment of high-risk patients determine survival, we… read more here.
Keywords: cancer; head neck; pni; cancer patients ... See more keywords
Interobserver reproducibility of perineural invasion of prostatic adenocarcinoma in needle biopsies
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DOI: 10.1007/s00428-021-03039-z
Abstract: Numerous studies have shown a correlation between perineural invasion (PNI) in prostate biopsies and outcome. The reporting of PNI varies widely in the literature. While the interobserver variability of prostate cancer grading has been studied… read more here.
Keywords: interobserver reproducibility; pni; perineural invasion; pathology ... See more keywords
Detection of perineural invasion in prostate needle biopsies with deep neural networks
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DOI: 10.1007/s00428-022-03326-3
Abstract: The presence of perineural invasion (PNI) by carcinoma in prostate biopsies has been shown to be associated with poor prognosis. The assessment and quantification of PNI are, however, labor intensive. To aid pathologists in this… read more here.
Keywords: biopsy; prostate; deep neural; neural networks ... See more keywords
Does preoperative prognostic nutrition index predict surgical site infection after spine surgery?
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DOI: 10.1007/s00586-020-06622-1
Abstract: Malnutrition is reported as one of the risk factors for surgical site infection (SSI). The prognostic nutritional index (PNI) is a simple method for nutritional evaluation. However, little is known about the relationship between SSI… read more here.
Keywords: spine surgery; surgery; index; ssi ... See more keywords
The prognostic nutritional index is correlated negatively with the lung allocation score and predicts survival after both cadaveric and living-donor lobar lung transplantation
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DOI: 10.1007/s00595-021-02244-2
Abstract: The prognostic nutritional index (PNI), calculated based on the serum albumin levels and the total lymphocyte count, has been identified as a predictor of clinical outcomes in various fields of surgery. In this study, we… read more here.
Keywords: prognostic nutritional; pni; nutritional index; lung transplantation ... See more keywords
Clinical significance of prognostic nutritional index (PNI) in malignant melanoma
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DOI: 10.1007/s10147-019-01461-7
Abstract: PurposeNutrition and inflammation play a crucial role in the development of cancer. The prognostic value of the prognostic nutritional index (PNI) has been confirmed in some types of human cancers. However, few studies are available… read more here.
Keywords: index; index pni; pni; malignant melanoma ... See more keywords