LAUSR

PNPLA3 downregulation exacerbates the fibrotic response in human hepatic stellate cells

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0 Published in 2021 at "PLoS ONE"

DOI: 10.1371/journal.pone.0260721

Abstract: Non-alcoholic steatohepatitis (NASH) results, in part, from the interaction of metabolic derangements with predisposing genetic variants, leading to liver-related complications and mortality. The strongest genetic determinant is a highly prevalent missense variant in patatin-like phospholipase… read more here.

Keywords: expression; stellate cells; pnpla3; hepatic stellate ... See more keywords