PNPLA3 rs738409 and risk of fibrosis in NAFLD: Exploring mediation pathways through intermediate histological features
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DOI: 10.1002/hep.32491
Abstract: It is unclear whether rs738409 (p.I148M) missense variant in patatin‐like phospholipase domain‐containing 3 rs738409 promotes fibrosis development by triggering specific fibrogenic pathways or by creating an unfavorable microenvironment by promoting steatosis, inflammation, and ultimately fibrosis.… read more here.
Keywords: pnpla3 rs738409; fibrosis nafld; rs738409 risk; risk fibrosis ... See more keywords
Higher Levels of Plasma Hyaluronic Acid and N-terminal Propeptide of Type III Procollagen Are Associated With Lower Kidney Function in Children With Non-alcoholic Fatty Liver Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.917714
Abstract: Objective Hyaluronic acid (HA) and N-terminal propeptide of type III procollagen (PIIINP) are two non-invasive biomarkers of liver fibrosis in non-alcoholic fatty liver disease (NAFLD). We examined the relationships of plasma levels of HA and… read more here.
Keywords: terminal propeptide; pnpla3 rs738409; acid terminal; hyaluronic acid ... See more keywords