Interaction of the Lysophospholipase PNPLA7 with Lipid Droplets through the Catalytic Region
Sign Up to like & getrecommendations! Published in 2020 at "Molecules and Cells"
DOI: 10.14348/molcells.2020.2283
Abstract: Mammalian patatin-like phospholipase domain containing proteins (PNPLAs) play critical roles in triglyceride hydrolysis, phospholipids metabolism, and lipid droplet (LD) homeostasis. PNPLA7 is a lysophosphatidylcholine hydrolase anchored on the endoplasmic reticulum which associates with LDs through… read more here.
Keywords: pnpla7 lds; pnpla7; catalytic region; interaction lysophospholipase ... See more keywords
Insulin, dibutyryl-cAMP, and glucose modulate expression of patatin-like domain containing protein 7 in cultured human myotubes
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1139303
Abstract: Expression of patatin-like phospholipase domain containing protein 7 (PNPLA7), also known as neuropathy target esterase-related esterase (NRE), a lysophospholipase, increases with fasting and decreases with feeding in mouse skeletal muscle, indicating it is regulated by… read more here.
Keywords: cultured human; expression; pnpla7; skeletal muscle ... See more keywords
The Lysophospholipase PNPLA7 Controls Hepatic Choline and Methionine Metabolism
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DOI: 10.3390/biom13030471
Abstract: The in vivo roles of lysophospholipase, which cleaves a fatty acyl ester of lysophospholipid, remained unclear. Recently, we have unraveled a previously unrecognized physiological role of the lysophospholipase PNPLA7, a member of the Ca2+-independent phospholipase… read more here.
Keywords: methionine metabolism; pnpla7; methionine; choline methionine ... See more keywords