Ghrelin modulates intracellular signalling pathways that are critical for podocyte survival
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DOI: 10.1002/cbf.3397
Abstract: Damage to podocytes is a key event in glomerulopathies. While energy dense food can contribute to kidney damage, the role of the orixegenic hormone “ghrelin” in podocyte biology is still unknown. In the present study,… read more here.
Keywords: p38 mapk; podocyte survival; ghrelin;
GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death.
Sign Up to like & getrecommendations! Published in 2018 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2017.11.006
Abstract: Progressive kidney diseases affect approximately 500 million people worldwide. Podocytes are terminally differentiated cells of the kidney filter, the loss of which leads to disease progression and kidney failure. To date, there are no therapies… read more here.
Keywords: podocyte survival; brafv600e inhibitor; gdc 0879; kidney ... See more keywords