Roles of the CLEC-2–podoplanin interaction in tumor progression
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DOI: 10.1080/09537104.2018.1478401
Abstract: Abstract Podoplanin is a type-I transmembrane sialomucin-like glycoprotein expressed on the surface of several kinds of tumor cells. The podoplanin receptor is a platelet activation receptor known as C-type lectin-like receptor 2 (CLEC-2), which has… read more here.
Keywords: clec podoplanin; podoplanin interaction; tumor cells; tumor ... See more keywords
High‐throughput screen identifies MAS9 as a novel inhibitor of the C‐type lectin receptor‐2 (CLEC‐2)–podoplanin interaction
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DOI: 10.1111/bph.70036
Abstract: The C‐type lectin‐like receptor‐2 (CLEC‐2) is a platelet receptor for the endogenous ligand podoplanin. This interaction contributes to several (patho)physiological processes, such as lymphangiogenesis, preservation of blood and lymphatic vessel integrity organ development, and tumour… read more here.
Keywords: receptor; clec; podoplanin interaction; receptor clec ... See more keywords