POEMS syndrome: An elusive diagnosis
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DOI: 10.1002/ajh.24845
Abstract: A 61-year-old female, with lower-extremity paresthesias and weakness of 9-month duration, was diagnosed with chronic inflammatory demyelinating polyneuropathy (CIDP). Initial evaluation revealed bilateral foot drop, areflexia, sensorimotor neuropathy with a demyelinating component, an elevated cerebrospinal… read more here.
Keywords: syndrome elusive; hematology; diagnosis; elusive diagnosis ... See more keywords
Outcomes of allogeneic transplantation after hypomethylating agents with venetoclax in acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26524
Abstract: plasma cells: first, antibody-mediated cellular cytotoxicity (complement-dependent cytotoxicity, antibody-dependent cellular phagocytosis, antibody-dependent cellular cytotoxicity), second, killing of immunosuppressive populations of T-regulatory and B-regulatory lymphocytes, and myeloid-derived suppressor cells that express CD38 and lastly immunomodulation mediated… read more here.
Keywords: agents venetoclax; poems syndrome; hypomethylating agents; allogeneic transplantation ... See more keywords
Osteolytic-variant POEMS syndrome: an uncommon presentation of “osteosclerotic” myeloma
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DOI: 10.1007/s00256-017-2607-8
Abstract: Polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes (POEMS) syndrome, a form of osteosclerotic myeloma, is a multisystem disease related to a monoclonal plasma cell proliferative disorder. Osseous lesions are most commonly sclerotic on radiographs… read more here.
Keywords: variant poems; syndrome uncommon; osteolytic variant; poems syndrome ... See more keywords
Reversal of skin changes in smoldering myeloma with clinical presentation of POEMS syndrome with a lenalidomide-based regimen
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Hematology"
DOI: 10.1007/s00277-019-03818-4
Abstract: Dear editor, POEMS (Takatsuki or Crow-Fukase syndrome), the acronym for polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes, is a rare multi systemic disorder [1]. It affects men more often than women and usually presents… read more here.
Keywords: smoldering myeloma; skin; clinical presentation; poems syndrome ... See more keywords
Glomeruloid hemangioma and POEMS syndrome.
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DOI: 10.1016/j.ad.2015.10.020
Abstract: POEMS syndrome is a paraneoplastic manifestation associated with hematopoietic disorders such as multiple myeloma and Castleman disease. POEMS is an acronym for the main clinical features of the syndrome, namely, Polyneuropathy, Organomegaly, Endocrinopathy, M protein,… read more here.
Keywords: hemangioma poems; glomeruloid hemangioma; poems syndrome;
POEMS Syndrome: Therapeutic Options.
Sign Up to like & getrecommendations! Published in 2018 at "Hematology/oncology clinics of North America"
DOI: 10.1016/j.hoc.2017.09.011
Abstract: Treatment of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome should be directed at the underlying plasma cell clone with risk-adapted therapy based on the extent of the plasma cell disorder. Radiation therapy… read more here.
Keywords: syndrome therapeutic; therapy; therapeutic options; poems syndrome ... See more keywords
The Peripheral Neuropathies of POEMS Syndrome and Castleman Disease.
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DOI: 10.1016/j.hoc.2017.09.012
Abstract: Polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, skin changes (POEMS) syndrome is a rare paraneoplastic disorder. The polyneuropathy can be the presenting symptom and is typically a painful, motor-predominant polyradiculoneuropathy often mimicking chronic inflammatory demyelinating… read more here.
Keywords: peripheral neuropathies; syndrome castleman; castleman disease; neuropathies poems ... See more keywords
Plexogenic pulmonary hypertension associated with POEMS syndrome
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DOI: 10.1016/j.rmcr.2017.08.011
Abstract: Pulmonary hypertension is one of the well-known clinical manifestations of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome, occurring in approximately 25–30% of the affected individuals. However, the histopathologic spectrum of pulmonary hypertension… read more here.
Keywords: hypertension associated; pulmonary hypertension; associated poems; plexogenic pulmonary ... See more keywords
Impact of pretransplant induction therapy on autologous stem cell transplantation for patients with newly diagnosed POEMS syndrome
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DOI: 10.1038/leu.2017.27
Abstract: POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes) is a rare plasma cell dyscrasia sometimes treated with a haematopoietic cell autotransplant. We analyzed data from 138 subjects with newly diagnosed POEMS syndrome receiving… read more here.
Keywords: newly diagnosed; year; diagnosed poems; poems syndrome ... See more keywords
Validation of a prognostic score for patients with POEMS syndrome: a mayo clinic cohort
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DOI: 10.1038/leu.2017.68
Abstract: We read with interest the manuscript by Wang et al. describing and validating a prognostic score for overall survival (OS) for patients with POEMS syndrome. The authors used four easily determined parameters to stratify patients… read more here.
Keywords: risk; prognostic score; study; poems syndrome ... See more keywords
Evidence‐based medical treatment of POEMS syndrome
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DOI: 10.1111/bjh.18400
Abstract: POEMS syndrome is a rare multisystem paraneoplastic disorder due to an underlying low‐level plasma cell dyscrasia. Due to its rarity, there are limited data to guide treatment and there are no consensus guidelines. Therapy choices… read more here.
Keywords: poems syndrome; evidence based; based medical; treatment ... See more keywords