How Can Chemometrics Support the Development of Point of Need Devices?
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DOI: 10.1021/acs.analchem.0c04151
Abstract: The necessity to establish novel solutions for decentralized monitoring is attracting attention in all fields of analytical chemistry, i.e., clinical, pharmaceutical, environmental, agri-food. The research around the terms "point-of-need", "point-of-care", "lab-on-chip", "biosensor", "microfluidics", etc. is/has… read more here.
Keywords: chemometrics support; support development; point need; chemistry ... See more keywords
Toward a Point-of-Need Bioluminescence-Based Immunoassay Utilizing a Complete Shelf-Stable Reagent.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c05074
Abstract: Enzyme-linked immunosorbent assays (ELISAs) are used extensively for the detection and quantification of biomolecules in clinical diagnostics as well as in basic research. Although broadly used, the inherent complexities of ELISAs preclude their utility for… read more here.
Keywords: bioluminescence based; based immunoassay; reagent; point need ... See more keywords
Emerging nanosensor platforms and machine learning strategies toward rapid, point-of-need small-molecule metabolite detection and monitoring
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DOI: 10.1039/d2sc02981b
Abstract: Speedy, point-of-need detection and monitoring of small-molecule metabolites are vital across diverse applications ranging from biomedicine to agri-food and environmental surveillance. Nanomaterial-based sensor (nanosensor) platforms are rapidly emerging as excellent candidates for versatile and ultrasensitive… read more here.
Keywords: nanosensor platforms; small molecule; detection; point need ... See more keywords
Handheld Raman Spectrometer Instrumentation for Quantitative Tuberculosis Biomarker Detection: A Performance Assessment for Point-of-Need Infectious Disease Diagnostics
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DOI: 10.1177/0003702818770666
Abstract: Techniques for the detection of disease biomarkers are key components in the protection of human health. While work over the last few decades has redefined the low-level measurement of disease biomarkers, the translation of these… read more here.
Keywords: detection; point need; disease; performance ... See more keywords
Progress and Challenges of Point-of-Need Photonic Biosensors for the Diagnosis of COVID-19 Infections and Immunity
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DOI: 10.3390/bios12090678
Abstract: The new coronavirus disease, COVID-19, caused by SARS-CoV-2, continues to affect the world and after more than two years of the pandemic, approximately half a billion people are reported to have been infected. Due to… read more here.
Keywords: point need; covid; life; photonic biosensors ... See more keywords
An Experimental Framework for Developing Point-of-Need Biosensors: Connecting Bio-Layer Interferometry and Electrochemical Impedance Spectroscopy
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DOI: 10.3390/bios12110938
Abstract: Biolayer interferometry (BLI) is a well-established laboratory technique for studying biomolecular interactions important for applications such as drug development. Currently, there are interesting opportunities for expanding the use of BLI in other fields, including the… read more here.
Keywords: spectroscopy; development; point need; framework ... See more keywords