Paf1C regulates RNA polymerase II progression by modulating elongation rate
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1904324116
Abstract: Significance The factors that regulate RNA polymerase II (Pol II) elongation rate and processivity are poorly understood. Here, we show that the Paf1 complex (Paf1C) modulates Pol II elongation rate, and loss of Paf1 results… read more here.
Keywords: pol elongation; rna polymerase; elongation; rate ... See more keywords
Nucleotide-level linkage of transcriptional elongation and polyadenylation
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DOI: 10.7554/elife.83153
Abstract: Alternative polyadenylation yields many mRNA isoforms whose 3’ termini occur disproportionately in clusters within 3’ UTRs. Previously, we showed that profiles of poly(A) site usage are regulated by the rate of transcriptional elongation by RNA… read more here.
Keywords: elongation; nucleotide level; transcriptional elongation; polyadenylation ... See more keywords