RNA Polymerase 1 Is Transiently Regulated by Seizures and Plays a Role in a Pharmacological Kindling Model of Epilepsy
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DOI: 10.1007/s12035-018-0989-9
Abstract: Ribosome biogenesis, including the RNA polymerase 1 (Pol1)-mediated transcription of rRNA, is regulated by the pro-epileptogenic mTOR pathway. Therefore, hippocampal Pol1 activity was examined in mouse models of epilepsy including kainic acid- and pilocarpine-induced status… read more here.
Keywords: ribosome content; rna polymerase; pol1; rrna ... See more keywords
Variability in Adaptive Resistance of Salmonella Typhimurium to Sublethal Levels of Antibiotics
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DOI: 10.3390/antibiotics11121725
Abstract: This study was designed to evaluate the adaptive resistance of Salmonella Typhimurium under continuous sublethal selective pressure. Salmonella Typhimurium ATCC 19585 (STATCC) and S. Typhimurium CCARM 8009 (STCCARM) were sequentially cultured for 3 days at… read more here.
Keywords: salmonella typhimurium; typhimurium; adaptive resistance; pol1 ... See more keywords