The root bark of Morus alba L. regulates tumor‐associated macrophages by blocking recruitment and M2 polarization of macrophages
Sign Up to like & getrecommendations! Published in 2020 at "Phytotherapy Research"
DOI: 10.1002/ptr.6783
Abstract: Tumor‐associated macrophages (TAMs) promote tumor growth and metastasis, and are closely related with poor prognosis of cancers. Therefore, TAMs have been an attractive target in cancer therapy. This study investigated whether the root bark of… read more here.
Keywords: tumor associated; polarization macrophages; polarization; bark morus ... See more keywords
Fusobacterium nucleatum promotes M2 polarization of macrophages in the microenvironment of colorectal tumours via a TLR4-dependent mechanism
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-018-2233-x
Abstract: Fusobacterium nucleatum (Fn) has been shown to promote colorectal cancer (CRC) development by inhibiting host anti-tumour immunity. However, the impact of Fn infection on macrophage polarization and subsequent intestinal tumour formation as well as the… read more here.
Keywords: tlr4 dependent; polarization macrophages; infection; dependent mechanism ... See more keywords
The improvement of M1 polarization in macrophages by glycopeptide derived from Ganoderma lucidum
Sign Up to like & getrecommendations! Published in 2017 at "Immunologic Research"
DOI: 10.1007/s12026-017-8893-3
Abstract: Ganodermalucidum (Fr.) Karst (Ganodermataceae) is a medicinal mushroom that has been extensively used in China for centuries to promote longevity and improve vigor without significant adverse effects. There is continuous interest in the bioactive properties… read more here.
Keywords: glycopeptide derived; derived ganoderma; polarization macrophages; macrophages glycopeptide ... See more keywords
M2 polarization of macrophages by Oncostatin M in hypoxic tumor microenvironment is mediated by mTORC2 and promotes tumor growth and metastasis.
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.03.032
Abstract: Oncostatin M (OSM), an inflammatory cytokine belonging to the interleukin-6 (IL-6) superfamily, plays a vital role in multitude of physiological and pathological processes. Its role in breast tumor progression and metastasis to distant organs is… read more here.
Keywords: tumor; distant organs; polarization macrophages; polarization ... See more keywords
Berberine attenuates arthritis in adjuvant‐induced arthritic rats associated with regulating polarization of macrophages through AMPK/NF‐&kgr;B pathway
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2019.02.036
Abstract: ABSTRACT Berberine (BBR) is a traditional folk medicine with excellent anti‐inflammatory properties. This study aimed to investigate the anti‐arthritic effects of BBR in adjuvant arthritis (AA) in rats and its regulatory role in the polarization… read more here.
Keywords: kgr pathway; polarization macrophages; regulating polarization; macrophages ampk ... See more keywords
Multi-walled carbon nanotubes induce arachidonate 5-lipoxygenase expression and enhance the polarization and function of M1 macrophages in vitro
Sign Up to like & getrecommendations! Published in 2023 at "Nanotoxicology"
DOI: 10.1080/17435390.2023.2204161
Abstract: Abstract Fibrogenic carbon nanotubes (CNTs) induce the polarization of M1 and M2 macrophages in mouse lungs. Polarization of the macrophages regulates the production of proinflammatory and pro-resolving lipid mediators (LMs) to mediate acute inflammation and… read more here.
Keywords: carbon nanotubes; expression; multi walled; polarization ... See more keywords
TNFSF15 facilitates differentiation and polarization of macrophages toward M1 phenotype to inhibit tumor growth
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2032918
Abstract: ABSTRACT Macrophages of the M2 phenotype in malignant tumors significantly aid tumor progression and metastasis, as opposed to the M1 phenotype that exhibits anti-cancer characteristics. Raising the ratio of M1/M2 is thus a promising strategy… read more here.
Keywords: polarization macrophages; tumor; differentiation polarization; macrophages toward ... See more keywords
PD27-05 POLARIZATION OF MACROPHAGES FROM M0 TO M2 WHEN SEEDED UPON GENIPIN-CROSSLINKED COLLAGEN MESH FOR TREATMENT OF STRESS URINARY INCONTINENCE
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000884.05
Abstract: INTRODUCTION AND OBJECTIVE:The immunological response of the body to implanted biomaterials remains a significant issue. Several important urogynecological applications (Stress Urinary Incontinence... read more here.
Keywords: stress urinary; macrophages seeded; polarization macrophages; urinary incontinence ... See more keywords
IL-6 influences the polarization of macrophages and the formation and growth of colorectal tumor
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24734
Abstract: Macrophages play a crucial role in tumorigenesis depending upon the phenotype of macrophages found in tumor microenvironments. To date, how the tumor microenvironment affects the phenotypes of macrophages is not yet fully understood. In this… read more here.
Keywords: influences polarization; macrophages formation; polarization macrophages; polarization ... See more keywords
α-Mangostin Inhibited M1 Polarization of Macrophages/Monocytes in Antigen-Induced Arthritis Mice by Up-Regulating Silent Information Regulator 1 and Peroxisome Proliferators-Activated Receptor γ Simultaneously
Sign Up to like & getrecommendations! Published in 2023 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s397914
Abstract: Background α-Mangostin (MG) showed the potentials in alleviating experimental arthritis, inhibiting inflammatory polarization of macrophages/monocytes, and regulating peroxisome proliferators-activated receptor γ (PPAR-γ) and silent information regulator 1 (SIRT1) signals. The aim of this study was… read more here.
Keywords: macrophages monocytes; ppar; sirt1 ppar; polarization macrophages ... See more keywords
UCHL1 Promoted Polarization of M1 Macrophages by Regulating the PI3K/AKT Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s343487
Abstract: Background As deubiquitinases (DUBs), ubiquitin C-terminal hydrolase (UCH)-L1 has been shown to play a crucial role in regulating diverse biological processes. However, its function in macrophage polarization remains unclear. Methods We performed in vivo and… read more here.
Keywords: uchl1 promoted; promoted polarization; expression; macrophages regulating ... See more keywords