Suppressive effects on lung fibrosis and the polarization and populations of macrophages by liposomal clodronate combined with pirfenidone
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DOI: 10.1016/j.freeradbiomed.2018.04.338
Abstract: Purpose Effective treatment of idiopathic pulmonary fibrosis (IPF) is still difficult. Macrophages (Mφ) are closely related to IPF. M1 phenotype Mφ exhibit proinflammatory properties, M2 phenotype Mφ promote fibrogenesis. We found that pirfenidone (PFD), a… read more here.
Keywords: liposomal clodronate; fibrosis; polarization populations; lung fibrosis ... See more keywords