miR-30b-5p releases HMGB1 via UBE2D2/KAT2B/HMGB1 pathway to promote pro-inflammatory polarization and recruitment of macrophages.
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DOI: 10.1016/j.atherosclerosis.2021.02.016
Abstract: BACKGROUND AND AIMS Oxidized low-density lipoprotein (ox-LDL) is a key risk factor for atherosclerosis, but there are few reports on ox-LDL-mediated inflammation after injury. In this study, we investigated the effects of ox-LDL on endothelial… read more here.
Keywords: pro inflammatory; mir 30b; polarization recruitment;