Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins
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DOI: 10.1073/pnas.1821076116
Abstract: Significance Epithelial cells perform critical protective, secretory, absorptive, and sensory functions, for which they require plasma membrane polarization into apical and basolateral domains. Impaired polarity causes cancer and developmental and degenerative disorders. Research on fundamental… read more here.
Keywords: surface proteins; surface; polarity; apical basolateral ... See more keywords