Articles with "pole mutated" as a keyword



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Phase II study of durvalumab monotherapy in patients with previously treated microsatellite instability‐high/mismatch repair‐deficient or POLE‐mutated metastatic or unresectable colorectal cancer

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Published in 2022 at "International Journal of Cancer"

DOI: 10.1002/ijc.33966

Abstract: The aim of our study is to evaluate the clinical efficacy of durvalumab in patients with microsatellite instability‐high/mismatch repair‐deficient (MSI‐H/dMMR) or polymerase epsilon (POLE)‐mutated metastatic or unresectable colorectal cancer (mCRC) who had disease progression after… read more here.

Keywords: microsatellite instability; study; response; cancer ... See more keywords