Articles with "polg mutant" as a keyword



Molecular signature of cardiac remodeling associated with Polymerase Gamma mutation.

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Published in 2022 at "Life sciences"

DOI: 10.1016/j.lfs.2022.120469

Abstract: AIMS Metabolic function/dysfunction is central to aging biology. This is well illustrated by the Polymerase Gamma (POLG) mutant mouse where a key residue of the mitochondrial DNA polymerase is mutated (D257A), causing loss of mitochondrial… read more here.

Keywords: polg mutant; dysfunction; polymerase gamma; polymerase ... See more keywords