The fabrication of cryogel scaffolds incorporated with poloxamer 407 for potential use in the regeneration of the nucleus pulposus
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Materials Science: Materials in Medicine"
DOI: 10.1007/s10856-016-5824-0
Abstract: Degeneration of the nucleus pulposus (NP) is the primary cause of back pain in almost 80% of the world population. The current gold standard treatment for a degenerated NP is a spinal fusion surgery which… read more here.
Keywords: p407; use; nucleus pulposus; regeneration ... See more keywords
Synergism and antagonism in mixed monolayers: Brij S20/poloxamer 407 and Triton X-100/poloxamer 407 mixtures
Sign Up to like & getrecommendations! Published in 2018 at "Fluid Phase Equilibria"
DOI: 10.1016/j.fluid.2018.06.009
Abstract: Abstract Knowledge of nonideal behavior of surfactant mixtures of nonionic surfactants at air/aqueous solution interface is important in order to obtain surfactant mixtures with improved properties. In this work interfacial behavior of Brij S20/P407 and… read more here.
Keywords: triton 100; mixed monolayers; brij s20; s20 poloxamer ... See more keywords
Sustained release of ketorolac tromethamine from poloxamer 407/cellulose nanofibrils graft nanocollagen based ophthalmic formulations.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.08.143
Abstract: There has been extensive utilization of poloxamer 407 (PM) for the delivery of various ophthalmic drugs aimed at efficient ophthalmic drug delivery approach for longer precorneal residence time along with acceptable bioavailability of drugs. We… read more here.
Keywords: ketorolac tromethamine; poloxamer 407; release ketorolac; release ... See more keywords
Orodispersible Films Containing Ball Milled Aripiprazole-Poloxamer®407 Solid Dispersions.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.118955
Abstract: This research aimed at developing ODFs containing an antipsychotic drug - aripiprazole (ARP). ARP, as a BCS II class molecule, requires enhancing its water solubility prior to formulating. Therefore, a solid dispersion of ARP -… read more here.
Keywords: films containing; solid dispersions; drug; poloxamer 407 ... See more keywords
Electroacupuncture ameliorates poloxamer 407‐induced hyperlipidemia through suppressing hepatic SREBP‐2 expression in rats
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.04.016
Abstract: Aims: Acupuncture, particularly electroacupuncture (EA) has been shown to have the lipid‐lowering effects, but not completely investigated. The present study was aimed to examine whether EA could attenuate poloxamer‐407 (P‐407)‐induced hyperlipidemia in the rats and… read more here.
Keywords: srebp; 407 induced; expression; poloxamer 407 ... See more keywords
Poloxamer 407‐chitosan grafted thermoresponsive hydrogels achieve synchronous and sustained release of antigen and adjuvant from single‐shot vaccines
Sign Up to like & getrecommendations! Published in 2018 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12031
Abstract: Sustained‐release vaccine delivery systems may enhance the immunogenicity of subunit vaccines and reduce the need for multiple vaccinations. The aim of this study was to develop a thermoresponsive hydrogel using poloxamer 407‐chitosan (CP) grafted copolymer… read more here.
Keywords: chitosan grafted; 407 chitosan; single shot; sustained release ... See more keywords
Poloxamer-407-Co-Poly (2-Acrylamido-2-Methylpropane Sulfonic Acid) Cross-linked Nanogels for Solubility Enhancement of Olanzapine: Synthesis, Characterization, and Toxicity Evaluation
Sign Up to like & getrecommendations! Published in 2020 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-020-01694-0
Abstract: Current study is focused to enhance the solubility of poorly soluble drug olanzapine (OLZ) by nanogels drug delivery system, as improved solubility is one of the most important applications of nanosystems. Poor solubility is a… read more here.
Keywords: cross linked; acrylamido methylpropane; solubility enhancement; poloxamer 407 ... See more keywords
Pharmacokinetics of butorphanol tartrate in a long-acting poloxamer 407 gel formulation administered to Hispaniolan Amazon parrots (Amazona ventralis).
Sign Up to like & getrecommendations! Published in 2017 at "American journal of veterinary research"
DOI: 10.2460/ajvr.78.6.688
Abstract: OBJECTIVE To determine pharmacokinetics of butorphanol tartrate incorporated into poloxamer 407 (P407) after SC administration to Hispaniolan Amazon parrots (Amazona ventralis). ANIMALS 11 adult Hispaniolan Amazon parrots (6 males and 5 females; 11 to 27… read more here.
Keywords: hispaniolan amazon; amazon parrots; pharmacokinetics butorphanol; formulation ... See more keywords
An Overview on Thermosensitive Oral Gel Based on Poloxamer 407
Sign Up to like & getrecommendations! Published in 2021 at "Materials"
DOI: 10.3390/ma14164522
Abstract: In this review, we describe the application of thermosensitive hydrogels composed of poloxamer in medicine, especially for oral cavities. Thermosensitive hydrogels remain fluid at room temperature; at body temperature, they become more viscous gels. In… read more here.
Keywords: based poloxamer; drug; gel based; poloxamer 407 ... See more keywords
Poloxamer 407-Based Thermosensitive Emulgel as a Novel Formulation Providing a Controlled Release of Oil-Soluble Pharmaceuticals—Ibuprofen Case Study
Sign Up to like & getrecommendations! Published in 2021 at "Materials"
DOI: 10.3390/ma14237266
Abstract: This article covers the design and evaluation of a novel drug vehicle: a thermosensitive, injectable, high-oil-content (50% w/w) emulgel providing a controlled release of lipophilic pharmaceuticals. Different vegetable (castor, canola, olive, peanut, grapeseed, linseed), mineral… read more here.
Keywords: providing controlled; release; emulgel; controlled release ... See more keywords
Poloxamer 407/188 Binary Thermosensitive Gel as a Moxidectin Delivery System: In Vitro Release and In Vivo Evaluation
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27103063
Abstract: Moxidectin (MXD) is an antiparasitic drug used extensively in veterinary clinics. In this study, to develop a new formulation of MXD, a thermosensitive gel of MXD (MXD-TG) was prepared based on poloxamer 407/188. Furthermore, the… read more here.
Keywords: poloxamer 407; moxidectin; vitro release; 407 188 ... See more keywords