Highlights in poloxamer-based drug delivery systems as strategy at local application for vaginal infections.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120635
Abstract: Infectious diseases related to the vagina include diseases caused by the imbalance of the vaginal flora and by sexually transmitted infections. Some of these present themselves as a public health problem due to the lack… read more here.
Keywords: drug delivery; delivery systems; poloxamer based; drug ... See more keywords
Conceptualization and Preliminary Characterization of Poloxamer-Based Hydrogels for Biomedical Applications
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DOI: 10.1021/acs.bioconjchem.5c00030
Abstract: Poloxamers are widely used in biomedical applications, but their effectiveness depends on achieving an optimal sol–gel phase transition near body temperature. This study evaluates three different poloxamer mixtures for their potential in treating meniscus tears,… read more here.
Keywords: characterization poloxamer; biomedical applications; poloxamer based; preliminary characterization ... See more keywords
Mode of action of poloxamer‐based surfactants in wound care and efficacy on biofilms
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DOI: 10.1111/iwj.12922
Abstract: Surfactants are widely used as detergents, emulsifiers, wetting agents, foaming agents, and dispersants in both the food and oil industry. Their use in a clinical setting is also common, particularly in wound care. Complicated or… read more here.
Keywords: poloxamer based; wound care; poloxamer; surfactants wound ... See more keywords
Mucoadhesive Poloxamer-Based Hydrogels for the Release of HP-β-CD-Complexed Dexamethasone in the Treatment of Buccal Diseases
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DOI: 10.3390/pharmaceutics13010117
Abstract: Oral lichen planus (OLP) is an ongoing and chronic inflammatory disease affecting the mucous membrane of the oral cavity. Currently, the treatment of choice consists in the direct application into the buccal cavity of semisolid… read more here.
Keywords: treatment; poloxamer based; xanthan gum; mucoadhesive poloxamer ... See more keywords
Investigation and Characterization of Factors Affecting Rheological Properties of Poloxamer-Based Thermo-Sensitive Hydrogel
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DOI: 10.3390/polym14245353
Abstract: Poloxamers are negatively temperature-sensitive hydrogels and their hydrophilic groups interact with water molecules at lower temperatures (liquid phase) while their hydrophobic groups interact more strongly with increases in temperature causing gelation. To investigate the factors… read more here.
Keywords: rheological properties; poloxamer based; affecting rheological; factors affecting ... See more keywords