Targeting Mitochondrial DNA Transcription by POLRMT Inhibition or Depletion as a Potential Strategy for Cancer Treatment
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DOI: 10.3390/biomedicines11061598
Abstract: Transcription of the mitochondrial genome is essential for the maintenance of oxidative phosphorylation (OXPHOS) and other functions directly related to this unique genome. Considerable evidence suggests that mitochondrial transcription is dysregulated in cancer and cancer… read more here.
Keywords: inhibition; polrmt; transcription; mitochondrial transcription ... See more keywords