Component effect of stem cell-loaded thermosensitive polypeptide hydrogels on cartilage repair.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.04.035
Abstract: Biophysical properties of the desired biomimetic scaffolds, such as porosity and elasticity, have been proven associated with the efficacy of cartilage regeneration. In this work, the copolymers of poly(l-alanine)-block-poly(ethylene glycol)-block-poly(l-alanine) (PA-PEG-PA) and poly(l-alanine-co-l-phenylalanine)-block-poly(ethylene glycol)-block-poly(l-alanine-co-l-phenylalanine) (PAF-PEG-PAF)… read more here.
Keywords: polypeptide hydrogels; thermosensitive polypeptide; phenylalanine; poly alanine ... See more keywords
The sequence context in poly-alanine regions: structure, function and conservation
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DOI: 10.1093/bioinformatics/btac610
Abstract: Abstract Motivation Poly-alanine (polyA) regions are protein stretches mostly composed of alanines. Despite their abundance in eukaryotic proteomes and their association to nine inherited human diseases, the structural and functional roles exerted by polyA stretches… read more here.
Keywords: structure function; polya; context; poly alanine ... See more keywords
Poly-Alanine-ε-Caprolacton-Methacrylate as Scaffold Material with Tuneable Biomechanical Properties for Osteochondral Implants
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23063115
Abstract: An aging population and injury-related damage of the bone substance lead to an increasing need of innovative materials for the regeneration of osteochondral defects. Biodegradable polymers form the basis for suitable artificial implants intended for… read more here.
Keywords: alanine caprolacton; poly alanine; caprolacton; osteochondral implants ... See more keywords