Tunability of Biodegradable Poly(amine- co-ester) Polymers for Customized Nucleic Acid Delivery and Other Biomedical Applications.
Sign Up to like & getrecommendations! Published in 2018 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.8b00997
Abstract: Gene therapy promises to treat diseases that arise from genetic abnormalities by correcting the underlying cause of the disease rather than treating the associated symptoms. Successful transfer of nucleic acids into cells requires efficient delivery… read more here.
Keywords: acid delivery; delivery; amine ester; nucleic acid ... See more keywords
Cellular determinants influence the red blood cell adsorption efficiency of poly(amine-co-ester) nanoparticles
Sign Up to like & getrecommendations! Published in 2025 at "Science Advances"
DOI: 10.1126/sciadv.adt8637
Abstract: Many poly(amine-co-ester) (PACE) nanoparticles, drug delivery vehicles for nucleic acid and small molecule cargoes, accumulate in the liver and spleen following intravenous administration, limiting delivery to nonhepatosplenic tissues. Red blood cell (RBC) hitchhiking, a strategy… read more here.
Keywords: adsorption; blood cell; poly amine; amine ester ... See more keywords
A Hybrid Material Based on Poly-3-Amine-7-Methylamine-2-Methylphenazine and Magnetite Nanoparticles
Sign Up to like & getrecommendations! Published in 2018 at "Nanotechnologies in Russia"
DOI: 10.1134/s1995078018020064
Abstract: For the first time, under the conditions of in situ oxidative polymerization, a hybrid dispersed magnetic material based on poly-3-amine-7-methylamine-2-methylphenazine (PAMMPh) is obtained in which nanoparticles Fe3O4 are dispersed in an electroactive polymer matrix. According… read more here.
Keywords: material based; based poly; amine methylamine; methylamine methylphenazine ... See more keywords