Delivery of Anti-microRNA-712 to Inflamed Endothelial Cells Using Poly(β-amino ester) Nanoparticles Conjugated with VCAM-1 Targeting Peptide.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202001894
Abstract: Endothelial cells (ECs) are an important target for therapy in a wide range of diseases, most notably atherosclerosis. Developing efficient nanoparticle (NP) systems that deliver RNA interference (RNAi) drugs specifically to dysfunctional ECs in vivo… read more here.
Keywords: mir 712; anti microrna; endothelial cells; amino ester ... See more keywords
Gamma irradiation, thermal conductivity, and phase change tests of the cement‐hyperbranched poly amino‐ester‐block‐poly cabrolactone‐polyurathane plaster‐lead oxide and arsenic oxide composite for development of radiation shielding material
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Energy Research"
DOI: 10.1002/er.7136
Abstract: The work which has been done on cement‐polymer composite based shielding materials was comprehensively described in the present article, the choice of the study presented here is based on the choice of the researches. The… read more here.
Keywords: block poly; ester block; poly amino; poly ... See more keywords
Secondary Structures in Synthetic Poly(Amino Acids): Homo- and Copolymers of Poly(Aib), Poly(Glu) and Poly(Asp).
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200344
Abstract: The secondary structure of poly(amino acids) is a major factor for controlling and understanding the functionality and properties of proteins. Investigations on model-homo-polyaminoacids represent an important contribution to understand folding or proteins. In this perspective… read more here.
Keywords: amino acids; glu; poly amino; homo ... See more keywords
Preparation of Ultrathin and Degradable Polymeric Films by Electropolymerization of 3-Amino-l-Tyrosine.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202200332
Abstract: Bioderived polymers are one of many current research areas that promise a sustainable future. Due to its unique properties, the bioderived polymer polydopamine has been in the spotlight over the last decades. Its ability to… read more here.
Keywords: amino tyrosine; preparation ultrathin; poly amino; electropolymerization ... See more keywords
Poly(amino acid)-based nanogel by horseradish peroxidase catalyzed crosslinking in an inverse miniemulsion
Sign Up to like & getrecommendations! Published in 2018 at "Colloid and Polymer Science"
DOI: 10.1007/s00396-018-4318-7
Abstract: We present an investigation of horseradish peroxidase (HRP)/H2O2-mediated crosslinking in an inverse miniemulsion for the successful preparation of a stable colloidal nanogel from a poly(amino acid)-based polymer precursor. The precursor was obtained by the aminolysis… read more here.
Keywords: acid based; amino acid; crosslinking inverse; inverse miniemulsion ... See more keywords
Hertzian elasticity and triggered swelling kinetics of poly(amino ester)-based gel beads with controlled hydrophilicity and functionality: A mild and convenient synthesis via dropwise freezing into cryogenic liquid
Sign Up to like & getrecommendations! Published in 2019 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2019.02.018
Abstract: Abstract Poly(amino ester)-based homo- and co-polymeric gel beads were prepared via “dropwise freezing into cryogenic liquid” method and multi-responsive properties of the prepared spherical beads were confirmed by the pulsatile swelling kinetics and the stress-strain… read more here.
Keywords: gel beads; gel; poly amino; amino ester ... See more keywords
Biocompatible fluorinated poly(β-amino ester)s for safe and efficient gene therapy.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.11.015
Abstract: Cationic polymers have been widely used as one of the most promising non-viral vehicles for gene delivery due to their potential safety and ease of large-scale production. Here, we report the design and synthesis of… read more here.
Keywords: fluorinated poly; ester; amino ester; poly amino ... See more keywords
Poly (β amino esters) Copolymers: Novel Potential Vectors for Delivery of Genes and Related Therapeutics.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.121289
Abstract: The unique properties of polymers have performed an essential contribution to the drug delivery system by providing an outstanding platform for the delivery of macromolecules and genes. However, the block copolymers have been the subject… read more here.
Keywords: novel potential; copolymers novel; delivery; amino esters ... See more keywords
Glycopolymer and Poly(β-amino ester)-Based Amphiphilic Block Copolymer as a Drug Carrier
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01076
Abstract: Glycopolymers are synthetic macromolecules having pendant sugar moieties and widely utilized to target cancer cells. They are usually considered as a hydrophilic segment of amphiphilic block copolymers to fabricate micelles as drug carriers. A novel… read more here.
Keywords: cell; amphiphilic block; poly amino; block copolymer ... See more keywords
Degradable Poly(amino acid) Vesicles Modulate DNA-Induced Inflammation after Traumatic Brain Injury.
Sign Up to like & getrecommendations! Published in 2023 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01334
Abstract: Following brain trauma, secondary injury from molecular and cellular changes causes progressive cerebral tissue damage. Acute/chronic neuroinflammation following traumatic brain injury (TBI) is a key player in the development of secondary injury. Rapidly elevated cell-free… read more here.
Keywords: inflammation; traumatic brain; poly amino; brain ... See more keywords
Synthesis and Characterization of Quaternized Poly(β-amino ester) for Highly Efficient Delivery of Small Interfering RNA.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b00549
Abstract: The development of non-viral vectors for gene delivery has gained attention over the past decades. Specifically, poly(β-amino ester) (PBAE) has shown great potential for improving the delivery of gene therapeutics. It has been observed that… read more here.
Keywords: delivery; amino ester; poly amino; gene ... See more keywords