An array of poly-l-histidine functionalized multi-walled carbon nanotubes on 4-aminothiophenol self-assembled monolayer and the application for sensitively glucose sensing
Sign Up to like & getrecommendations! Published in 2017 at "Electrochimica Acta"
DOI: 10.1016/j.electacta.2017.11.150
Abstract: Abstract Novel approachs to functionalize carboxylated multi-walled carbon nanotubes (CMWCNTs) array with poly- l -histidine (PLH) on a self-assembled monolayer (SAM) of 4-aminothiophenol (4ATP) were developed for the first time. With help of π–π interaction… read more here.
Keywords: array; walled carbon; carbon nanotubes; poly histidine ... See more keywords
Dual-Modality Poly-l-histidine Nanoparticles to Deliver Peptide Nucleic Acids and Paclitaxel for In Vivo Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2021 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c11981
Abstract: Cationic polymeric nanoformulations have been explored to increase the transfection efficiency of small molecules and nucleic acid-based drugs. However, an excessive positive charge density often leads to severe cell and tissue-based toxicity that restricts the… read more here.
Keywords: histidine; peptide nucleic; histidine nanoparticles; poly histidine ... See more keywords
Simultaneous enrichment and sequential separation of glycopeptides and phosphopeptides with poly-histidine functionalized microspheres
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1011851
Abstract: Protein phosphorylation and glycosylation coordinately regulate numerous complex biological processes. However, the main methods to simultaneously enrich them are based on the coordination interactions or Lewis acid-base interactions, which suffer from low coverage of target… read more here.
Keywords: simultaneous enrichment; poly histidine; sequential separation; enrichment sequential ... See more keywords
Prion Amyloid Polymorphs – The Tag Might Change It All
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2020.00190
Abstract: Sup35p is a protein from Saccharomyces cerevisiae. It can propagate using a prion-like mechanism, which means that it can recruit non-prion soluble Sup35p into insoluble fibrils. Sup35p is a large protein showing three distinct domains,… read more here.
Keywords: prion; poly histidine; prion amyloid; tag ... See more keywords
The polyHIS Tract of Yeast AMPK Coordinates Carbon Metabolism with Iron Availability
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021368
Abstract: Energy status in all eukaryotic cells is sensed by AMP-kinases. We have previously found that the poly-histidine tract at the N-terminus of S. cerevisiae AMPK (Snf1) inhibits its function in the presence of glucose via… read more here.
Keywords: poly histidine; metabolism; snf1; tract ... See more keywords
The Poly-Histidine Tag H6 Mediates Structural and Functional Properties of Disintegrating, Protein-Releasing Inclusion Bodies
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14030602
Abstract: The coordination between histidine-rich peptides and divalent cations supports the formation of nano- and micro-scale protein biomaterials, including toxic and non-toxic functional amyloids, which can be adapted as drug delivery systems. Among them, inclusion bodies… read more here.
Keywords: poly histidine; histidine tag; inclusion bodies; protein release ... See more keywords