Frontline Science: Estrogen‐related receptor γ increases poly(I:C)‐mediated type I IFN expression in mouse macrophages
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.2hi1219-762r
Abstract: Although type I IFNs (IFN‐I) are important for the innate and adaptive immune responses to suppress viral replication, prolonged IFN‐I signaling in macrophages suppresses the immune response. Nuclear receptor estrogen‐related receptor γ (ERRγ) regulates the… read more here.
Keywords: expression; related receptor; poly mediated; estrogen related ... See more keywords
Transactivation Domain of Human c-Myc Is Essential to Alleviate Poly(Q)-Mediated Neurotoxicity in Drosophila Disease Models
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DOI: 10.1007/s12031-017-0910-4
Abstract: Polyglutamine (poly(Q)) disorders, such as Huntington’s disease (HD) and spinocerebellar ataxias, represent a group of neurological disorders which arise due to an atypically expanded poly(Q) tract in the coding region of the affected gene. Pathogenesis… read more here.
Keywords: poly; poly mediated; transactivation domain; mediated neurotoxicity ... See more keywords