Mono- and Poly-unsaturated Phosphatidic Acid Regulate Distinct Steps of Regulated Exocytosis in Neuroendocrine Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.108026
Abstract: Specific forms of fatty acids are well known to have beneficial health effects, but their precise mechanism of action remains elusive. Phosphatidic acid (PA) produced by phospholipase D1 (PLD1) regulates the sequential stages underlying secretory… read more here.
Keywords: exocytosis neuroendocrine; mono poly; poly unsaturated; phosphatidic acid ... See more keywords
"Force-from-lipids" gating of mechanosensitive channels modulated by PUFAs.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2017.12.026
Abstract: The level of fatty acid saturation in phospholipids is a crucial determinant of the biophysical properties of the lipid bilayer. Integral membrane proteins are sensitive to changes of their bilayer environment such that their activities… read more here.
Keywords: lipids gating; poly unsaturated; ion; membrane ... See more keywords