Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation.
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DOI: 10.1016/j.celrep.2020.01.094
Abstract: Heterochromatin functions as a scaffold for factors responsible for gene silencing and chromosome segregation. Heterochromatin can be assembled by multiple pathways, including RNAi and RNA surveillance. We identified factors that form heterochromatin using dense profiles… read more here.
Keywords: polyadenylation factors; heterochromatin; cleavage polyadenylation; integration ... See more keywords
Alternative polyadenylation factors link cell cycle to migration
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DOI: 10.1186/s13059-018-1551-9
Abstract: BackgroundIn response to a wound, fibroblasts are activated to migrate toward the wound, to proliferate and to contribute to the wound healing process. We hypothesize that changes in pre-mRNA processing occurring as fibroblasts enter the… read more here.
Keywords: cleavage polyadenylation; quiescent fibroblasts; cell cycle; polyadenylation ... See more keywords